A - Human Necessities
61
K
A61K 39/095 (2006.01) A61K 39/02 (2006.01) A61K 39/102 (2006.01) A61K 39/116 (2006.01)
Patent
CA 2674345
The present invention relates to improved methods of conducting carbodiimide condensation reactions. In particular, it relates to the conjugation of saccharides (in particular the Vi capsular saccharide from Salmonella typhi) and proteins using carbodiimide condensation. It also relates to immunogenic compositions that may be made comprising the saccharide-protein conjugates of the invention.
La présente invention concerne des procédés améliorés de mise en oeuvre de réactions de condensation de carbodiimide. Cette invention concerne en particulier la conjugaison de saccharides (en particulier du saccharide capsulaire Vi de Salmonella typhi) et de protéines par condensation de carbodiimide. Cette invention concerne en outre des compositions immunogènes pouvant être produites à l'aide des conjugués saccharides-protéines de cette invention.
Biemans Ralph Leon
Duvivier Pierre
Glaxosmithkline Biologicals S.a.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
LandOfFree
Vaccine does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Vaccine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Vaccine will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1384901