Vaccine against avian encephalomyelitis

C - Chemistry – Metallurgy – 12 – N

Patent

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167/130, 195/33

C12N 7/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2000634

ABSTRACT VACCINE AGAINST AVIAN ENCEPHALOMYELITIS A process for preparation of an attenuated strain of avian encephalamyelitis virus ("AEV") which may be used as a component of a protective vaccinne, which comprises the steps of infecting chick embryo fibroblast ("CEF") cells with AEV, culturing the AEV- infected CEF cells until the AEV has become adapted to the CEF cells and then isolating the AEV product from the CEF cells for use in the vaccine. An attenutated AEV strain produced in this way, and tests showing use as a vaccine in chickens are also described.

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