A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/295 (2006.01) A61K 39/002 (2006.01) A61K 39/12 (2006.01) A61K 39/125 (2006.01) A61K 39/245 (2006.01) A61K 39/25 (2006.01) A61K 39/29 (2006.01) A61K 39/39 (2006.01)
Patent
CA 2384064
Novel combined vaccine compositions are provided, comprising a herpes simplex virus (HSV) antigen and a HPV antigen and optionally in addition one or more of the following: an EBV antigen, a hepatitis A antigen or inactivated attenuated virus, a hepatitis B viral antigen, a VZV antigen, a HCMV antigen, a Toxoplasma gondii antigen. The vaccine compositions are formulated with an adjuvant which is a preferential stimulator of TH1 cell response such as 3D-MPL and QS21.
La présente invention concerne de nouvelles compositions de vaccins associés qui comprennent un antigène de virus herpès simplex (HSV), un antigène de papillomavirus (HPV) et éventuellement un ou plusieurs des éléments suivants: un antigène du virus d'Epstein-Barr (EBV), un antigène ou un virus atténué inactivé d'hépatite A, un antigène viral d'hépatite B, un antigène de virus varicelle-zona (VZV), un antigène du cytomégalovirus humain (HCMV), un antigène de toxoplasme. Lesdites compositions de vaccins sont formulées avec un adjuvant qui est un stimulateur préférentiel de réponse de lymphocytes Th1, tel que 3D-MPL et QS21.
Borden Ladner Gervais Llp
Smithkline Beecham Biologicals S.a.
LandOfFree
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