Vaccine against mumps and process for its preparation

Details Vaccine against mumps and process for its preparation Vaccine against mumps and process for its preparation

Category

A - Human Necessities

Subcategory

61

Subsubcategory

K

CPC

167/130

IPC codes

A61K 39/165 (2006.01)

Type

Patent

Patent number

CA 1286226

Description

ABSTRACT OF THE DISCLOSURE The invention relates to a live vaccine against mumps, which contains live mumps viruses which are capable of multiplication and have been attenuated principally by passages in diploid human tissue cultures. The vaccine is substantially free from proteins and antibiotics. The invention also relates to the process for the preparation of a live vaccine against mumps, which comprises obtaining live mumps viruses from the urine of patients with an acute attack of mumps, passaging the viruses in diploid human cells, thereby attenuating the viruses by repeated passages in tissue of this type and, optionally further attenuating the viruses by passaging in embryonic or fertilized chicken eggs, optionally further attenuating the viruses by further passaging in diploid human cells, thereby adapting the viruses to human tissue, isolating, cultivating, and then processing the live mumps viruses.

Application Number

516928

Affiliated with

Also associated with

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