Vaccine against neisseria meningitidis infections

Details Vaccine against neisseria meningitidis infections Vaccine against neisseria meningitidis infections

A - Human Necessities

61

K

A61K 39/095 (2006.01) C07K 14/22 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2097056

ABSTRACT Vaccine against Neisseria meningitidis infections A vaccinal pharmaceutical composition which comprises, as therapeutic agents, at least a first and a second molecule capable of binding to human transferrin; the said first molecule originating from a first strain of N. meningitidis which possesses a human transferrin receptor in which the lower molecular weight subunit (Tbp2) is recognised by an antiserum to the receptor of N. meningitidis strain 2394 (receptor 2394) and is not recognised by an antiserum to the receptor of N. menin- gitidis strain 2169 (receptor 2169); and at least a second molecule originating from a second strain of N. meningitidis which possesses a human transferrin receptor in which the lower molecular weight subunit (Tbp2) is recognised by an anti-receptor 2169 antiserum and is not recognised by an anti-receptor 2394 antiserum.

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