Vaccine against rinderpest virus using recombinant vaccinia...

Details Vaccine against rinderpest virus using recombinant vaccinia... Vaccine against rinderpest virus using recombinant vaccinia...

C - Chemistry, Metallurgy

12

N

167/130, 195/1.2

C12N 15/35 (2006.01) A61K 39/155 (2006.01) C07K 14/115 (2006.01) C12N 15/863 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1313151

ABSTRACT OF THE DISCLOSURE A plasmid comprising a gene coding for an antigenic protein of the rinderpest virus and a viral promoter which can express that gene, as well as a gene derived from a vaccinia virus which is not essential for the growth of the vaccinia virus, wherein the gene coding for the antigenic protein and the viral promoter have been inserted in the gene not essential for the growth of the vaccinia virus; a recombinant vaccinia virus prepared by a recombination of the above-mentioned plasmid and a vaccinia virus; a process for the production of the recombinant vaccinia virus; a vaccine against the rinderpest virus, comprising the recombinant vaccinia virus; and a method for immunization of a mammal against rinderpest virus comprising injecting the mammals with the recombinant vaccinia virus.

579958

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