Vaccine against staphylococcus intoxication

Details Vaccine against staphylococcus intoxication Vaccine against staphylococcus intoxication

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 39/085 (2006.01) C07K 14/31 (2006.01) C12N 1/21 (2006.01) C12N 7/01 (2006.01) C12N 15/86 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2337966

Using nucleic acids encoding non-toxic mutant SEA and SEB exotoxins from Staphylococcus aureus, compositions and methods for use in inducing an immune response which is protective against staphylococcal aureus intoxication in subjects is described.

L'invention concerne des compositions et des procédés permettant d'induire une réponse immunitaire qui constitue une protection contre l'intoxication par les staphylocoques dorés. Ces compositions et ces procédés utilisent des acides nucléiques codant des exotoxines mutantes de type SEA et SEB.

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