Vaccine against varicella-zoster virus

Details Vaccine against varicella-zoster virus Vaccine against varicella-zoster virus

A - Human Necessities

61

K

167/130, 195/1.2

A61K 39/12 (2006.01) A61K 39/25 (2006.01) C07K 14/04 (2006.01) C12P 21/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1272456

VACCINE AGAINST VARICELLA-ZOSTER VIRUS ABSTRACT OF THE DISCLOSURE A gene of varicella-zoster virus (VZV) which encodes immunogenic outer surface viral proteins has been identified through DNA sequence analysis. Fragments of the DNA have been cloned into a vector which, when placed into a host organism, expresses proteins which react with human convalescent zoster sera and with monoclonal antibodies which neutralize viral infectivity. These proteins are useful for preparation of a vaccine for VZV.

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