A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 38/17 (2006.01)
Patent
CA 2546077
Methods and compositions are provided for treatment of neurodegenerative diseases in which there is accumulation of misfolded and/or aggregated proteins, excluding prion diseases. In particular, the invention relates to treatment of the neurodegenerative diseases Huntington's disease (HD), Alzheimer's disease (AD) or Parkinson's disease (PD), by administration of an agent selected from the group consisting of (i) Copolymer 1, (ii) a Copolymer 1-related peptide, (iii) a Copolymer 1-related polypeptide, and (iv) T cells activated with (i), (ii) or (iii).
La présente invention concerne des procédés et des compositions pour traiter des maladies neurodégénératives impliquant une accumulation de protéines mal repliées et/ou agrégées, à l'exception des maladies à prion. Elle concerne notamment le traitement de maladies neurodégénératives, telles que la maladie de Huntington (HD), la maladie d'Alzheimer (AD) ou la maladie de Parkinson (PD), grâce à l'administration d'un agent choisi dans le groupe formé par (i) un copolymère 1, (ii) un peptide lié à un copolymère 1, (iii) un polypeptide lié à un copolymère 1 et (iv) des lymphocytes T activés avec (i), (ii) ou (iii).
Butovsky Oleg
Eisenbach-Schwartz Michal
Kipnis Jonathan
Yoles Ester
Borden Ladner Gervais Llp
Ltd. Yeda Research And Development Co.
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