Vaccine and method of using

Details Vaccine and method of using Vaccine and method of using

A - Human Necessities

61

K

167/130

A61K 39/12 (2006.01) A61K 39/00 (2006.01) A61K 39/295 (2006.01)

Patent

CA 1073814

VACCINE AND METHOD OF USING ABSTRACT OF THE DISCLOSURE A virus-lysed tumor cell vaccine is an active immunotherapeutic agent against tumors in mammals. In particular, a vaccine based upon vaccinia virus-lysed, species-specific tumor cells is an effective stimulator of the immune response in mammals, and a vaccine based upon vaccinia virus-lysed spontaneously arising tum or cells is an effective stimulator of the immune response in some human cancer patients. A process for preparing the vaccine by viral oncolysis is also disclosed. Tumor cells are removed from a mammal, the cells are cultured in a culture medium and infected with live vaccinia virus. Viral oncolysis occurs during incubation and the resulting viral oncolysate, after extraction, may be injected into mammals to stimulate the immune response mechanism.

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