A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/21 (2006.01) A61K 39/39 (2006.01)
Patent
CA 2087732
2087732 9222654 PCTABS00018 An Acquired Immunodeficiency Syndrome (AIDS) vaccine containing the Human Immunodeficiency Virus, Type-1 (HIV-1) envelope proteins is produced from cloned HIV-1 envelope genes in a baculovirus-insect cell vector system. The recombinant HIV-1 proteins are purified, assembled into particles and then adsorbed on an aluminum phosphate adjuvant. The resulting adsorbed recombinant HIV-1 virus envelope protein formulation (AIDS vaccine) is highly immunogenic in animals and elicits antibodies which bind to the HIV-1 virus envelope and neutralize the infectivity of the virus in in vitro) tests. The above AIDS vaccine induces new humoral and cellular immune responses in HIV-infected patients and is useful as a form of vaccine therapy to delay or prevent the destruction of the immune system.
Smith Gale E.
Volvovitz Franklin
Barrigar & Moss
Microgenesys Inc.
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