A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/116 (2006.01) A61K 39/118 (2006.01) A61P 31/04 (2006.01) C07K 14/295 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2436435
The present invention relates to the field of Gram-negative bacterial vaccine compositions, their manufacture, and the use of such compositions in medicine. More particularly it relates to the field of useful Gram-negative bacterial outer membrane vesicle (or bleb) compositions comprising heterologously expressed Chlamydia antigens, and advantageous methods of rendering these compositions more effective and safer as a vaccine.
L'invention concerne des compositions vaccinales à base de bactéries à gram négatif, leur préparation, ainsi que leur utilisation en médecine. Plus particulièrement, l'invention concerne des compositions utiles de vésicules de membranes externes (bleb) de bactéries à gram négatif présentant une expression d'antigènes deChlamydia hétérologues, ainsi que des méthodes avantageuses permettant de rendre ces compositions plus efficaces et plus sûres comme vaccins.
Berthet Francois-Xavier Jacques
Lobet Yves
Poolman Jan
Verlant Vincent Georges Christian Louis
Glaxosmithkline Biologicals S.a.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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