Vaccine composition admixed with an alkylphosphatidylcholine

A - Human Necessities – 61 – K

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A61K 39/39 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2545086

The invention relates to a pharmaceutical composition comprising at least one vaccine antigen. The inventive composition is characterised in that it also comprises at least one phosphoric ester derivative of phosphatidylcholine with a structure having formula I, wherein: R1 is a lower alkyl; and R2 and R3 are identical or different and can each represent linear hydrocarbon chains having between 13 and 21 carbon atoms.

La présente invention concerne une composition pharmaceutique comprenant au moins un antigène vaccinal, caractérisée en ce qu~elle comprend en outre au moins un dérivé ester phosphorique de phosphatidylcholine ayant la structure (formule I), dans laquelle R¿1? est un alkyle inférieur, R¿2? et R¿3? sont identiques ou différents, et peuvent chacun représenter des chaînes linéaires hydrocarbonées ayant de 13 à 21 atomes de Carbone.

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