C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 19/28 (2006.01) A61K 31/70 (2006.01) A61K 39/00 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) C07H 15/10 (2006.01) C07K 16/30 (2006.01)
Patent
CA 2139217
The present invention relates to the active specific immunotherapy of cancer and among other things provides a vaccine composition for producing or increasing the antibody immune response against N-glycolylated gangliosides, especially N-glycolyl GM3 (NGcGM3), which can be used for the prevention and treatment of cancer. The vaccine composition comprises an adequate amount of N-glycolylated ganglioside and/or its derivatives and/or its corresponding oligosaccharide, coupled non covalently or covalently to adequate protein or protein complex carriers depending on the case, and containing additionally, any appropriate adjuvant.
Hernandez Oscar G. V.
Molina Luis E. F.
Perez Adriana C.
Rodriguez Gilda M.
Rodriguez Rolando P.
Centro de Inmunologia Molecular
Macrae & Co.
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