A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 39/04 (2006.01) A61K 39/21 (2006.01) A61P 31/18 (2006.01) A61P 33/06 (2006.01) A61P 37/04 (2006.01)
Patent
CA 2737761
The present invention relates, inter alia, to a method of raising an immune response against a pathogen which comprises administering (i) one or more first immunogenic polypeptides derived from said pathogen; (ii) one or more viral vectors comprising one or more heterologous polynucleotides encoding one or more second immunogenic polypeptides derived from said pathogen; and (iii) an adjuvant; wherein the one or more first immunogenic polypeptides, the one or more viral vectors and the adjuvant are administered concomitantly. The invention also relates to vaccines, pharmaceutical compositions, kits and uses employing said polypeptides, viral vectors and adjuvants.
La présente invention concerne, entre autres, un procédé dinduction dune réponse immunitaire contre un pathogène qui comprend ladministration de (i) un ou plusieurs premiers polypeptides immunogènes dérivés dudit pathogène; (ii) un ou plusieurs vecteurs viraux comprenant un ou plusieurs polynucléotides hétérologues codant pour un ou plusieurs seconds polypeptides immunogènes dérivés dudit pathogène; et (iii) un adjuvant; où les un ou plusieurs premiers polypeptides immunogènes, les un ou plusieurs vecteurs viraux et ladjuvant sont administrés concomitamment. Linvention concerne en outre des vaccins, des compositions pharmaceutiques, des trousses et des utilisations employant lesdits polypeptides, vecteurs viraux et adjuvants.
Fevrier Michele
Lorin Clarisse Marie-Madeleine
Tangy Frederic
Voss Gerald Hermann
Glaxosmithkline Biologicals S.a.
Gowling Lafleur Henderson Llp
Institut Pasteur
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