Vaccine compositions comprising virosomes and a saponin...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/145 (2006.01) A61K 9/127 (2006.01) A61K 39/39 (2006.01) A61K 47/46 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2565500

The invention provides virosome preparations from an enveloped virus, in particular from influenza virus, containing an antigen from said virus, and a saponin adjuvant. In particular the invention provides a virosome preparation from influenza virus containing an influenza antigen a QS21, optionally with a sterol. The invention also provides vaccine compositions containing said virosome preparations, methods of preparing said virosome preparations and vaccine containing them.

Cette invention concerne des préparations de virosomes à partir d'un virus enveloppé, en particulier, à partir du virus de la grippe, contenant un antigène provenant dudit virus, et un adjuvant à base de saponine. Plus particulièrement, cette invention concerne une préparation de virosomes à partir du virus de la grippe contenant un antigène de la grippe QS21, éventuellement avec un stérol. Cette invention concerne également des compositions de vaccins contenant les préparations de virosomes susmentionnées, des procédés permettant de préparer ces préparations de virosomes et un vaccin les contenant.

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