Vaccine compositions containing liposomes

Details Vaccine compositions containing liposomes Vaccine compositions containing liposomes

A - Human Necessities

61

K

A61K 39/39 (2006.01) A61K 9/00 (2006.01) A61K 9/107 (2006.01) A61K 9/127 (2006.01) A61K 39/015 (2006.01) A61K 39/145 (2006.01) A61K 39/21 (2006.01) A61K 39/245 (2006.01)

Patent

CA 2086094

A vaccine composition, comprising an antigenic substance in association with a liposome and an oil-in-water emulsion comprising a muramyl peptide, a metabolizable oil, and optionally an additional emulsifying agent. The two components of the adjuvant (i.e., the liposome/antigen component and the emulsion component) act together to produce high levels of immune response.

Composition de vaccin, comprenant une substance antigénique en association avec un liposome et une émulsion huile-dans-l'eau composée d'un peptide muramyle, d'une huile métabolisable, et éventuellement d'un agent émulsifiant supplémentaire. Les deux composants de l'adjuvant (c'est-à-dire le composant liposome/antigène et le composant émulsion) interagissent et produisent des niveaux de réponse immunitaire élevés.

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