A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/215 (2006.01) C07K 14/165 (2006.01)
Patent
CA 2572389
The present disclosure relates to compositions and methods for treating or preventing coronavirus infections. For example, compositions are provided that comprise a coronavirus S protein or N protein, fragment, or variant thereof, capable of eliciting a protective humoral and/or cell-mediated immune response, which compositions are useful for treating or preventing infection by coronavirus, such as the causative agent of SARS. Also, coronavirus S protein and N protein immunogen compositions are provided that include an adjuvant, such as Proteosome or Protollin, which may be used for treating or preventing infection caused by a coronavirus, such as a SARS coronavirus.
L'invention concerne des compositions et des procédés permettant de traiter ou de prévenir des infections par coronavirus. Cette invention concerne par exemple des compositions comprenant une protéine S ou une protéine N ou un fragment de coronavirus, ou une variante correspondante, et pouvant provoquer une réponse immunitaire protectrice à médiation humorale et/ou cellulaire. Lesdites compositions peuvent servir à traiter ou prévenir des infections par un coronavirus, tel que l'agent responsable du SARS. La présente invention se rapporte en outre à des compositions immunogènes comportant une protéine S et une protéine N de coronavirus, ainsi qu'un adjuvant tel que les adjuvants Protéosome ou Protollin, ces compositions pouvant servir à traiter ou prévenir une infection causée par un coronavirus tel qu'un coronavirus provoquant le SARS.
Burt David S.
Hu Mary Chaohong
Jones David Hugh
Lowell George H.
Reddish Mark A.
Borden Ladner Gervais Llp
Id Biomedical Corporation Of Quebec
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