A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/095 (2006.01) C07K 14/22 (2006.01)
Patent
CA 2488782
The present invention relates to vaccine compositions for the effective prevention or treatment of neisserial, preferably meningococcal, disease. The vaccines of the invention comprise a multivalent meningococcal bled composition comprising at least one bleb with homologous bactericidal activity which is derived from a meningococcal strain with a serosubtype that is prevalent in a country of use, and at least one bleb with heterologous bactericidal activity which is derived from a meningococcal strain which need not have a serosubtype that is prevalent in the country of use.
L'invention porte sur des vaccins efficaces de prévention ou de traitement de maladies à neisseria, ou de préférence à méningocoques. Lesdits vaccins contiennent une composition de boutons de méningocoques dont un au moins à activité bactéricide homologue dérivant d'une souche de méningocoques comportant un séro-soustype prévalant dans le pays d'utilisation, et un au moins à activité bactéricide hétérologue dérivant d'une souche de méningocoques ne devant pas comporter de séro-soustype prévalant dans le pays d'utilisation.
Barbera Morales Ramon Faustino
Desmons Pierre Michel
Dominguez Alvarez Francisco Jesus
Poolman Jan
Glaxosmithkline Biologicals S.a.
Instituto Finlay
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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