Vaccine for periodontal disease

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/02 (2006.01)

Patent

CA 2565925

The present invention relates to novel bacterial isolates identified by their 16S rRNA DNA, that cause periodontal disease in companion animals, polynucleotide sequences contained therein, polypeptides encoded by such polynucleotide sequences and vaccines comprising such bacteria, polynucleotides, or polypeptides. Also provided are methods for treating and preventing periodontal disease and kits for detecting and treating periodontal disease kits for detecting and preventing periodontal disease. In addition, methods for assessing the efficacy of a vaccine against periodontal diseases in an animal are provided.

L'invention concerne de nouveaux isolats bactériens identifiés par leur ADN à ARNr 16S, qui provoquent les parodontopathies chez les animaux de compagnie, les séquences polynucléotidiques contenues, les polypeptides codés par ces séquences polynucléotidiques et les vaccins contenant ces bactéries, ces polynucléotides ou ces polypeptides. L'invention concerne également des méthodes permettant de traiter et de prévenir les parodontopathies ainsi que des trousses permettant de détecter et de traiter les parodontopathies, des trousses permettant de détecter et de prévenir les parodontopathies. L'invention concerne en outre des méthodes permettant d'évaluer l'efficacité d'un vaccin contre les parodontopathies chez un animal.

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