Vaccine strains of brachyspira hyodysenteriae

Details Vaccine strains of brachyspira hyodysenteriae Vaccine strains of brachyspira hyodysenteriae

A - Human Necessities

61

K

A61K 39/02 (2006.01) A61P 1/00 (2006.01) C12Q 1/04 (2006.01) C12Q 1/25 (2006.01) C12Q 1/68 (2006.01) G01N 33/48 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2743660

The present invention relates generally to vaccine strains of Brachyspira hyodysenteriae. In particular, the present invention relates to isolated live vaccine strains of B. hyodysenteriae lacking one or more virulence factors. The present invention also relates to methods of identifying and preparing vaccine strains, as well as vaccine compositions against diarrhoeal diseases and methods and kits for diagnosing same.

La présente invention concerne généralement des souches de vaccin de Brachyspira hyodysenteriae. En particulier, la présente invention concerne des souches de vaccin vivant isolées de B. hyodysenteriae ne comportant pas un ou plusieurs facteurs de virulence. La présente invention concerne en outre des procédés didentification et de préparation de souches de vaccin, ainsi que des compositions de vaccin contre des maladies diarrhéiques et des procédés et kits pour diagnostiquer celles-ci.

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