Vaccines against aids comprising cmv/r-nucleic acid constructs

Details Vaccines against aids comprising cmv/r-nucleic acid constructs Vaccines against aids comprising cmv/r-nucleic acid constructs

C - Chemistry, Metallurgy

07

K

C07K 14/16 (2006.01) A61K 39/21 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2573702

The present disclosure provides compositions for eliciting an immune response, including a prophylactic immune response, against human immunodeficiency virus. The composition includes nucleic acid constructs encoding HIV antigenic polypeptides of multiple clades or strains. Methods for eliciting an immune response by administering the composition to a subject are also provided.

L'invention concerne des compositions permettant de provoquer une réaction immunitaire, notamment une réaction immunitaire prophylactique, contre le virus de l'immunodéficience humaine. La composition de l'invention comprend des constructions d'acides nucléiques codant pour des polypeptides antigéniques du VIH de multiples variantes ou souches. L'invention concerne également des procédés permettant de provoquer une réaction immunitaire par administration de ladite composition à un sujet.

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