Vaccines against diseases, caused by reo-virus, and process...

A - Human Necessities – 61 – K

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A61K 39/17 (2006.01) A61K 39/15 (2006.01) A61K 39/295 (2006.01)

Patent

CA 1136043

ABSTRACT OF THE DISCLOSURE Vaccines derived from aviair reo-virus to combat aberra- tions of the skeleton such as rachitis - like symptoms, osteoporose c.q. femur degeneration diarrhea and growth inhibition, a process for their preparation, combined, inactivated vaccines, ready for administration and active against at least Newcastle disease and aberrations of the skeleton, diarrhea and growth inhibition and process for the preparation of such vaccine. The combined vaccine is prepared by addition of a Newcastle disease virus (NDV) containing liquid, obtained by cultivation of a NDV, followed by inactivation of this liquid and optionally homogenizing it, together with a reo-virus containing liquid, obtained by culti- vation of a reo-virus, followed by inactivation of this liquid and optionally homogenizing it, to an oily phase containing as essential components at least one of the components selected from the group consisting of light mineral oils, light paraffinic mineral oils, plant oils, vegetable oils, and naphtenic mineral oils and one or more emulsifiers, such as non-ionic surface- active compound derived from alkylene oxide and/or hexahydric alcohols and/or higher natural fatty acids such as esters or ester-ethers, optionally followed by homogenizing and/or addition of a preservative.

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