C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/57 (2006.01) A01K 67/033 (2006.01) A61K 39/00 (2006.01) C07K 14/435 (2006.01) C07K 16/40 (2006.01) C07K 16/42 (2006.01) C12N 9/64 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2140673
The present invention provides novel metazoan parasite antigens, nucleic acids encoding them and their use in the control of disease caused by helminth and other metazoan parasites, particularly helminth and arthropod parasites in domestic animals. In particular the invention provides a protective metazoan parasite antigen or antigenic fragments, components or precursors thereof and functionally-equivalent derivatives, analogues or variants thereof having protective antigenic activity against one or more metazoan parasites, which antigen is characterised by being capable of binding to pepstatin, and which in native form is an integral membrane protein or protein complex. Also provided are antigens characterised by aspartyl proteinase-like and/or neu- tral endopeptidase-like activity.
Knox David P.
Liddell Susan
Murray Jacqueline
Smith Stuart K.
Smith William D.
Kirby Eades Gale Baker
Mallinckrodt Veterinary Inc.
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