Vaccines against neisseria meningitidis

Details Vaccines against neisseria meningitidis Vaccines against neisseria meningitidis

A - Human Necessities

61

K

A61K 39/095 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2592156

Various polypeptides, or a variant or fragment thereof or a fusion of these are described which are useful in a vaccine. The polypeptide may be a polypeptide comprising the amino acid sequence selected from any one of SEQ ID Nos (2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44, 46, 48, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68); or a fragment or variant thereof or a fusion of such fragment or variant, and is useful in a vaccine against Neisseira meningitidis.

L'invention porte sur divers polypeptides ou un variant ou un fragment de ceux-ci ou sur la fusion du variant ou du fragment, ces polypeptides étant utiles dans un vaccin. Le polypeptide peut-être un polypeptide comprenant la séquence d'acides aminés sélectionnés parmi une quelconque de ces séquences: SEQ ID Nos (2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44, 46, 48, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68). L'invention porte également sur un fragment ou un variant de ces polypeptides ou sur une fusion de ce fragment ou de ce variant qui est utile dans un vaccin pour lutter contre Neisseira meningitidis.

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