Vaccines and agents for inducing immunity in fish against...

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 15/11 (2006.01) A61K 39/02 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2339327

The use of the 17 kDa outer surface lipoprotein (OspA) of Piscirickettsia salmonis, or its homologues, as the basis of, or part thereof, a recombinant vaccine for salmonid rickettsial septicaemia and other rickettsial diseases is disclosed. Surface antigens of the bacterial pathogen P. salmonis are characterized and an immunoreactive antigen, namely the 17 kDa outer surface lipoprotein OspA of P. salmonis, as well as the nucleic acid segment that encodes the OspA immunoreactive antigen, is identified and characterized. Diagnostic techniques including the use of hybridization probes and primers as well as the production of specific antigens and antibodies that may be used in immunization techniques for inducing immunity against P. salmonis and other rickettsial diseases are disclosed, as are the development of recombinant vaccines for SRS and other rickettsial diseases based on the 17 kDa lipoprotein OspA. Augmentation of protective immunity by the inclusion of promiscuous T lymphocyte epitopes (TCE's) in fusion protein constructs in salmonids and to the use of bacterial protein inclusion bodies as a source of the protective immunogen is also disclosed.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Vaccines and agents for inducing immunity in fish against... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Vaccines and agents for inducing immunity in fish against..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Vaccines and agents for inducing immunity in fish against... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-2075665

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.