Vaccines and methods for their production

Details Vaccines and methods for their production Vaccines and methods for their production

C - Chemistry, Metallurgy

12

N

C12N 7/04 (2006.01) A61K 39/12 (2006.01) A61K 39/21 (2006.01) A61K 39/39 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2068817

ABSTRACT The present invention relates to the production of vaccines having improved safety, particularly to a process therefor which allows even an AIDS vaccine to be manufactured, comprising in order, the steps of: a) treating the virus with a general inactivating agent; b) deaggreaging the virus with a suitable solvent or detergent; c) treating the virus with an RNA and/or DNA inactivating agent; and d) stabilising the virus with a suitable cross-linking agent.

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