Vaccines and methods to treat canine influenza

A - Human Necessities – 61 – K

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A61K 39/145 (2006.01) A61P 31/16 (2006.01)

Patent

CA 2621320

The present invention relates to providing new vaccines and treatments for the diseases related to canine influenza virus. It discloses influenza viral antigens, and methods of presenting these antigens to canines, especially dogs. It relates to attenuated and killed vaccines. The present invention relates to experimentally generated canine and equine influenza viruses. The invention also includes influenza A, including H3, N8, H3N8, H7N7 and viruses which contain at least one genome segment from an canine or equine influenza virus. The present invention also relates to the use of these viruses in therapeutic compositions to protect canines, dogs in particular, from diseases caused by influenza viruses.

La présente invention concerne des nouveaux vaccins et des nouveaux traitements destinés à des maladies associées au virus de la grippe canine. Cette invention concerne des antigènes viraux de la grippe ainsi que des méthodes permettant mettre en contact ces antigènes avec des canidés, plus particulièrement des chiens. L'invention concerne des vaccins inactivés ou atténués. La présente invention concerne des virus de la grippe équine et canine produits de manière expérimentale. En outre, l'invention concerne le virus de la grippe A, y compris les virus H3, N8, H3N8, H7N7 ainsi que les virus contenant au moins un segment génomique provenant du virus de la grippe équine ou canine. On décrit également l'utilisation de ces virus dans des compositions thérapeutiques afin de protéger les canidés et plus particulièrement les chiens, contre des maladies provoquées par les virus de la grippe.

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