Vaccines based on modified type 1 bovine herpesviruses

Details Vaccines based on modified type 1 bovine herpesviruses Vaccines based on modified type 1 bovine herpesviruses

C - Chemistry, Metallurgy

12

N

C12N 7/00 (2006.01) A61K 39/245 (2006.01) A61K 39/42 (2006.01) C07K 14/03 (2006.01) C07K 14/06 (2006.01) C07K 16/10 (2006.01) C12N 15/10 (2006.01) C12N 15/38 (2006.01) C12P 21/08 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2085191

The present invention relates to vaccines based on type 1 bovine herpesviruses (BHV-1) which contain modifi- cations in regions of their genome which code for non- essential parts of essential proteins. It is possible with the aid of these vaccines to differentiate immunised from non-immunised cattle. The invention furthermore relates to processes for the isolation and preparation of the modified BHV-1 strains, isolation and preparation of the modified proteins and peptides.

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