C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/85 (2006.01) A61K 39/21 (2006.01) A61K 39/245 (2006.01) A61K 39/39 (2006.01) A61K 48/00 (2006.01) C07K 14/52 (2006.01) C07K 14/54 (2006.01)
Patent
CA 2322160
Improved vaccines which include a nucleotide sequence that encodes immunomodulating protein operably linked to regulatory elements are disclosed. The improved vaccines include DNA vaccines, recombinant vaccines for delivering foreign antigen and live attenuated vaccines. Methods of immunizing individuals are disclosed. Compositions for and methods of treating individuals with autoimmune diseases are disclosed.
L'invention concerne des vaccins améliorés comprenant une séquence nucléotide codant pour des protéines immunomodulatrices liées coopérantes à des éléments de régulation. Les vaccins améliorés comprennent des vaccins ADN, des vaccins recombinants pour l'apport d'antigènes étrangers et des vaccins vivants atténués. L'invention concerne également des procédés d'immunisation d'individus, ainsi que des compositions et des procédés de traitement d'individus atteints d'affections auto-immunes.
Kim Jong J.
Sin Jeong-Im
Weiner David B.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
The Trustees Of The University Of Pennsylvania
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