Vaccines using pattern recognition receptor-ligand:lipid...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/39 (2006.01) A61K 9/127 (2006.01) A61L 29/08 (2006.01) A61L 29/16 (2006.01) A61N 5/00 (2006.01)

Patent

CA 2532140

This invention relates to a vaccine and a method for immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in a mammal. The method is particularly effective for protecting a mammal from a disease including cancer, a disease associated with allergic inflammation, an infectious disease, or a condition associated with a deleterious activity of a self- antigen. Also disclosed are therapeutic compositions useful in such a method.

La présente invention concerne un vaccin et un procédé d'activation immunitaire qui est efficace pour provoquer à la fois une réponse immunitaire systémique non spécifique à l'antigène et une réponse immunitaire forte spécifique à l'antigène chez un mammifère. Ce procédé est particulièrement efficace pour protéger un mammifère d'une maladie telle que le cancer, d'une maladie associée à une inflammation allergique, d'une maladie infectieuse ou d'une pathologie associée à une activité délétère d'un auto-antigène. La présente invention concerne également des compositions thérapeutiques utilisées dans le cadre de ce procédé.

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