Vaccinia vectors, vaccinia genes and expression products...

Details Vaccinia vectors, vaccinia genes and expression products... Vaccinia vectors, vaccinia genes and expression products...

C - Chemistry, Metallurgy

12

N

167/130, 167/37,

C12N 15/86 (2006.01) A61K 39/285 (2006.01) C07K 14/07 (2006.01) C07K 14/705 (2006.01) C12N 9/00 (2006.01) C12N 15/12 (2006.01) C12N 15/52 (2006.01) C12N 15/863 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2033200

VACCINIA VECTORS, VACCINIA GENES AND EXPRESSION PRODUCTS THEREOF ABSTRACT The invention discloses recombinant vaccinia virus vectors wherein a) part or all of one or more of the following nucleotide sequences is deleted from the viral genome; and/or b) one or more of said nucleotide sequences is inactivated by mutation or the insertion of foreign DNA; and/or c) one or more of said nucleotide sequences is changed to alter the function of the protein product encoded by said nucleotide sequence, which nucleotide sequences are sequences designated herein as i) Sal F 3R ii) Sal F 9R iii) Sal F 13R iv) B5R v) Sal F 15R.

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