C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A61K 35/76 (2006.01) A61K 39/275 (2006.01) C07K 14/07 (2006.01) C12N 5/10 (2006.01) C12N 15/69 (2006.01) C12N 15/863 (2006.01) A61K 35/00 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2489301
The invention concerns an Avipoxvirus comprising in the viral genome a Vaccinia virus host range gene or a homologue of said host range gene. The invention futher relates to cells, preferably avian cells, comprising a Vaccinia virus host range gene or a homologue of said host range gene. Moreover the invention concerns the use of a Vaccinia virus host range gene or an homologue thereof to increase the titer of avipoxviruses produced from cells after infection of said cells with the avipoxvirus, wherein the host range gene is expressed in said cells.
L'invention concerne un Avipoxvirus contenant le génome viral d'un gène hôte du virus de la vaccine ou un homologue dudit gène hôte. L'invention porte aussi sur des cellules, de préférence des cellules aviaires, contenant un gène hôte du virus de la vaccine ou un homologue dudit gène hôte. De plus, l'invention concerne l'utilisation d'un gène hôte du virus de la vaccine ou un homologue de ce dernier permettant d'augmenter le titre des avipoxvirus produits à partir des cellules après l'infection de ces dernières avec l'avipoxvirus, le gène hôte étant exprimé dans lesdites cellules.
Howley Paul
Meisinger-Henschel Christine
Bavarian Nordic A/s
Goudreau Gage Dubuc
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