Vaginal ring

A - Human Necessities – 61 – K

Patent

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167/153, 128/51

A61K 47/00 (2006.01) A61F 6/08 (2006.01) A61K 9/00 (2006.01) A61M 31/00 (2006.01)

Patent

CA 1165239

ABSTRACT OF THE DISCLOSURE A vaginal ring comprises a supporting ring free of active agent. A layer, which contains an active agent such as a steroid, is applied on its outer rim, optionally in a continuous groove provided in the supporting ring. This layer, in turn, is coated with a layer devoid of active ingredient. All components pre- ferably comprise an LTV silicon elastomer. The ratio of the thickness of the layer, containing an active agent, to the layer, free of active agent, is about 5-50 : 1. As a result, a long- term and uniform release rate is achieved for the active agent.

388832

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