Vaginal ring iii

Details Vaginal ring iii Vaginal ring iii

A - Human Necessities

61

F

128/51

A61F 13/20 (2006.01) A61F 6/08 (2006.01) A61K 9/00 (2006.01) A61M 31/00 (2006.01)

Patent

CA 1084792

ABSTRACT OF THE DISCLOSURE The present invention provides in a composite vaginal ring containing a safe and effective amount of a pharmaceutically active medicament which includes: a) a major supporting medicament-free vaginal ring consisting essentially of a physio- locigally acceptable synthetic resin and having at least a portion of the annular surface thereof adapted to mate with a correspond- ing minor, medicament-containing vaginal ring segment; and b) at least one minor, medicament-containing vaginal ring segment adapted to mate with the modified annular surface of said major supporting vaginal ring and consisting essentially of a safe and effective amount of a pharmaceutically active non-ionic, lipophilic drug dissolved or uniformly suspended in an elasto- meric, cross-linked LTV linear dimethylpolysiloxane resin, the improvement wherein: at least one of the major supporting vaginal ring and the minor vaginal ring segment has a reniform or ellipsoidal cross section; or the major supporting vaginal ring is formed as a closed or inwardly open hollow-profile ring, as a closed or inwardly open hollow ring, as a hollow ring having a circular or reniform cross section, as a core-encased composite ring or as a sandwich element.

275656

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