Valproic acid conjugates

Details Valproic acid conjugates Valproic acid conjugates

C - Chemistry, Metallurgy

07

C

C07C 233/47 (2006.01) A61K 31/19 (2006.01) C07C 237/22 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2241853

The present invention provides glutamate and glutamine conjugates of valproic acid. Synthetic methods are also provided for preparing the conjugates. Methods are provided for identifying the conjugates in biological samples, including urine, serum and CSF of patients treated with VPA, using synthetic conjugates as standards.

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