Valve for osmotic devices

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/22 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2402637

An osmotic delivery system for controlled delivery of a beneficial agent includes an implant capsule having a beneficial agent reservoir, an osmotic agent which expands on contact with fluid imbibed through a permeable membrane retained by the implant capsule, a delivery port, and a valve for opening and closing the delivery port. When the osmotic agent expands, a pressure is exerted against a separating member positioned between the beneficial agent reservoir and the osmotic agent. The separating member moves within the capsule, thereby forcing the valve to move a distance such that the beneficial agent can exit the reservoir through the delivery port.

L'invention concerne un système d'administration osmotique pouvant réguler l'administration d'une substance utile. Le système d'administration osmotique comprend une capsule implantable munie d'un réservoir de la substance utile, une substance osmotique qui se répand au contact d'un fluide imbibé à travers une membrane perméable retenue par la capsule implantable, un orifice de décharge, et une clapet pour ouvrir ou fermer l'orifice de décharge. Lorsque la substance osmotique se répand, une pression s'exerce contre un élément de séparation placé entre le réservoir de la substance utile et la substance osmotique. L'élément de séparation se déplace à l'intérieur de la capsule forçant ainsi la clapet à se déplacer sur une distance, de sorte que la substance utile puisse s'extraire du réservoir par l'orifice de décharge.

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