Vampire bat plasminogen activators

Details Vampire bat plasminogen activators Vampire bat plasminogen activators

C - Chemistry, Metallurgy

12

N

530/13, 167/139,

C12N 15/12 (2006.01) A61K 38/16 (2006.01) C07K 1/26 (2006.01) C07K 14/435 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/72 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1341090

Highly active glycoprotein plasminogen activators which exhibit a stringent requirement for the presence of a fibrin cofactor, and which readily catalyze the lysis of plasma clots. The plasminogen activator can be produced by host microorganisms or eukaryotic cells which have been transformed by expression vectors haying an inserted DNA sequence encoding the glycoprotein.

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