Variable current density single needle electroporation...

A - Human Necessities – 61 – N

Patent

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A61N 1/32 (2006.01) A61N 1/30 (2006.01) C12M 1/42 (2006.01)

Patent

CA 2710408

This invention comprises an improved electroporation electrode system comprising a single needle and a ring or donut shaped electrode wherein the difference in surface area of the electrodes provide for a substantial reduction of current density near the surface of the treated tissue and a more concentrated current density sufficient for electroporation only in tissues adjacent to the terminal portion of the single needle electrode. Thus, this invention provides for targeting specific tissue for electroporation and also should provide for lessening the sensation of electric current in the treated tissue.

L'invention porte sur un système d'électrode d'électroporation amélioré qui comporte une aiguille unique et une électrode en forme d'anneau ou de beignet, la différence de surface des électrodes fournissant une réduction sensible de densité de courant à proximité de la surface du tissu traité et une densité de courant plus concentrée suffisante pour une électroporation seulement dans les tissus adjacents à la partie terminale de l'électrode à aiguille unique. Ainsi, l'invention porte sur un ciblage de tissu spécifique pour une électroporation et devrait également entraîner la diminution de la sensation de courant électrique dans le tissu traité.

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