C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2571567
The present invention provides novel method for increasing the efficiency and accuracy of high-throughput mutation mapping and genome resequencing by using a variable length probe selection algorithm to rationally select probes used in designing oligonucleotide arrays synthesized by Maskless Array Synthesis (MAS) technology. Also disclosed is a variable length probe selection algorithm used in designing such oligonucleotide arrays.
Un nouveau procédé d'amélioration de l'efficacité de la précision d'un mappage de mutation haut rendement et d'un reséquençage de génome au moyen d'un algorithme de sélection de sonde à longueur variable afin de sélectionner rationnellement des sondes utilisées dans la conception de matrices oligonucléotidiques synthétisées par la technologie de synthèse de matrice sans masque. Un algorithme de sélection de sonde à longueur variable utilisé dans la conception de telles matrices oligonucléotidiques.
Albert Thomas J.
Green Roland
Norton Jason
Gowling Lafleur Henderson Llp
Nimblegen Systems Inc.
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