A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/38 (2006.01) A61L 2/16 (2006.01) A61L 27/36 (2006.01) A61K 35/34 (2006.01)
Patent
CA 2640762
Non-glutaraldehyde fixation of an organ or a prosthesis for implantation in a mammal is based upon carbodiimide treatment. A solution containing a sterilizing agent, such as EDC, in combination with a coupling enhancer, such as Sulfo-NHS, and a high concentration of a diamine cross linking agent is used. As a result, only minimal surface reduction occurs during fixation, and the resultant products show a dramatic increase in resistance to calcification.
Selon l'invention, attachement non glutaraldéhyde d'un organe ou d'une prothèse pour implantation dans un mammifère est basé sur un traitement à la carbodiimide. On utilise une solution contenant un agent stérilisant, tel que dichlorure d'éthylène, en combinaison avec un amplificateur de couplage, tel que du Sulfo-NHS, et une haute concentration en agent diamine réticulé. En conséquence, seule une réduction de surface minime se produit pendant la fixation, et les produits résultants présentent une augmentation dramatique de la résistance à la calcification.
Girardot Jean-Marie
Girardot Marie-Nadia
Biomedical Design Inc.
Fetherstonhaugh & Co.
LandOfFree
Variably crosslinked tissue does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Variably crosslinked tissue, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Variably crosslinked tissue will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1750619