Variant iaspp polypeptide and screening assay

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/47 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2617559

We disclose a screening assay for the identification of agents that inhibit the interaction of p53 with p53 inhibitory polypeptides and including p53 inhibitory polypeptide variants that are inactive with respect to the inhibition of p53 activity.

L'invention concerne un essai de criblage destiné à l'identification d'agents inhibant l'interaction de p53 avec des poypeptides inhibiteurs de p53, notamment des variants de polypeptides inhibiteurs de p53 inactifs par rapport à l'inhibition de l'activité de p53.

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