C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/273, 260/266
C07D 471/04 (2006.01)
Patent
CA 1105020
Abstract Various 1,5,6,11-tetrahydrobenzo[5,6]cyclohepta[1,2-b]- pyrazolo[4,3-el]pyridine derivatives and their salts of the formulas Image and Image wherein R1 is lower alkyl, phenyl, or phenyl-lower alkyl: R2 is hydrogen, lower alkyl or phenyl; R3 is hydrogen, halogen, or lower alkoxy; R4 is hydrogen, Image , or Image alkyl; R5 is hydrogen or lower a1koxy; R6 is hydrogen, Image , Image , Image , or Image ; n is an integer from 2 to 6; R7 and R8 are the same or different and each is lower alkyl or R7 and R8 taken together with the N-atom form a heterocyclic ring of the formula Image , Image , or Image wherein R9 is hydrogen or lower alkyl; R10 and R11 are the same or different and each is hydrogen or lower alkyl or R10 and R11 taken together with the N-atom form a heterocyclic ring of the formula Image , Image , or Image wherein R9 is as defined above; are disclosed. These compounds possess useful anti- inflammatory activity as well as psychotropic activity.
292448
Bernstein Jack
Hoehn Hans
Vogt Berthold R.
Osler Hoskin & Harcourt Llp
Squibb (e.r.) & Sons Inc.
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