Variously substituted derivatives of guanidine, and their...

C - Chemistry – Metallurgy – 07 – C

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C07C 279/12 (2006.01) A61K 31/155 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) C07C 279/04 (2006.01) C07C 279/18 (2006.01) C07C 281/16 (2006.01) C07D 295/215 (2006.01)

Patent

CA 2506685

Formula (I) compounds are described where the groups are as identified in the text, and their use as medicines, particularly as anti-diabetes, serum glucose- lowering and anti-obesity agents. Said medicines are useful for the prophylaxis and treatment of diabetes, particularly type 2 diabetes, and its complications, syndrome X, the various forms of insulin resistance, and hyperlipidaemias, as well as for the treatment of obesity.

L'invention concerne des composés de formule (I) dans laquelle les groupes sont tels que définis dans le texte et leur utilisation comme médicaments, plus particulièrement comme médicaments permettant de lutter contre le diabète, d'abaissement du taux de glucose sérique et d'agents anti-obésité. Ces médicaments sont utilisés dans la prophylaxie et le traitement du diabète, particulièrement du diabète de type II et ses complications, du syndrome X, des diverses formes insulinorésistances et d'hyperlipidémies, ainsi que dans le traitement de l'obésité

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