Vascular graft prosthesis and method for making same

A - Human Necessities – 61 – L

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3/121, 167/327

A61L 27/24 (2006.01) A61L 33/00 (2006.01) A61F 2/00 (2006.01)

Patent

CA 1119351

ABSTRACT A method is provided for controlling thrombogeni- city of a vascular graft prosthesis by controlling the surface charge of at least the intimal surface of the pros- thesis by reaction with a compound selected from the group consisiting of albumin, succinic anhydride, glyoxals, ethoxy- formic anhydride, formic acid, and 1-ethyl-3-(3-dimethyl- aminopropyl) carbodiimide. The surface charge is then stabi- lized by treatment with glutaraldehyde, dialdehyde starch, or formalin.

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