Ve-cadherin promoter and its uses

Details Ve-cadherin promoter and its uses Ve-cadherin promoter and its uses

C - Chemistry, Metallurgy

12

N

C12N 15/00 (2006.01) A01K 67/027 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2272994

The invention concerns the cloning of the VE-cadherin promoter. It also concerns the transformed cells and the transgenic animals containing said promoter. This promoter is particularly useful for the tissue-specific expression of a gene of interest in the vascular endothelium.

L'invention est relative au clonage du promoteur de la VE-cadhérine. L'invention concerne également des cellules transformées et des animaux transgéniques comprenant ledit promoteur. Ce promoteur est en particulier utilisable pour l'expression tissu-spécifique d'un gène d'intérêt dans l'endothélium vasculaire.

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