Vector and method of use for nucleic acid delivery to...

Details Vector and method of use for nucleic acid delivery to... Vector and method of use for nucleic acid delivery to...

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C12N 7/01 (2006.01)

Patent

CA 2233867

A recombinant retrovirus capable of infecting a non-dividing cell and a method of producing such a virus is provided. The recombinant retrovitrus is preferably of lentivirus origin and is useful for the treatment of a variety of disorders including neurological disorders and disorders of other non- dividing cells.

L'invention concerne un rétrovirus recombinant capable d'infecter une cellule ne subissant pas de division, ainsi qu'un procédé de production de ce virus. Ce rétrovirus recombinant est, de préférence, d'origine lentivirus et est utile pour traiter une variété de maladies, y compris des troubles neurologiques et des maladies d'autres cellules ne subissant pas de division.

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