Vector comprising a replication competent hiv-1 provirus and...

Details Vector comprising a replication competent hiv-1 provirus and... Vector comprising a replication competent hiv-1 provirus and...

C - Chemistry, Metallurgy

12

N

167/46, 195/1.17

C12N 15/86 (2006.01) C07K 14/16 (2006.01) C12N 15/867 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 1336075

A vector comprising an HIV segment and a heterologous gene segment, which produces a replication competent and an infective HIV virus is disclosed. When the heterologous gene is a marker gene, the spread of the virus can be observed in both in vitro and in vivo systems. The use of this vector in established methods for screening anti-viral compounds is also disclosed.

613694

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