Vector for integration of heterologous sequences into...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/86 (2006.01) A61K 39/285 (2006.01) C07K 14/07 (2006.01) C12N 15/39 (2006.01) C12N 15/863 (2006.01)

Patent

CA 2372709

The present invention provides a DNA vector comprising a nucleic acid sequence useful for inserting heterologous sequences into the genome of poxviruses by homologous recombination. The present invention relates also, <i>inter alia</i>, to recombinant poxviruses carrying heterologous coding sequences transferred by the vector according to the present invention.

L'invention concerne un vecteur d'ADN comprenant des séquences d'acides nucléiques utiles dans l'insertion de séquences hétérologues dans le génome de poxvirus, par recombinaison homologue. L'invention concerne également, entre autres, des poxvirus recombinés, porteurs des séquences de codage hétérologues transférées par le vecteur de l'invention.

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