Vectorization of dsrna by cationic particles and their use...

A - Human Necessities – 61 – K

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A61K 31/713 (2006.01) A61K 8/60 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2547127

La présente invention se rapporte à la vectorisation d'oligonucléotide d'ARN double brin par des particules cationiques choisies parmi des micelles de tensioactifs, des micelles de polymères blocs ou non, des liposomes et niosomes cationiques, des oléosomes cationiques, des nanoémulsions cationiques, ainsi que des particules organiques ou inorganiques cationiques et les nanocapsules, et à l'utilisation des compositions comprenant l'association d'au moins un dsRNA et d'au moins une particule cationique sur des modèles de peau ainsi qu'à des kit comprenant l'association d'au moins un dsRNA et d'au moins une particule cationique et au moins un modèle de peau.

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